Related Experiment Video
Updated: Jan 29, 2026

Zebrafish Model of Neuroblastoma Metastasis
Published on: March 14, 2021
Neuroblastoma with an unusual ovarian metastasis in a 5-year-old girl
Carla Steytler1, Ahmed A Darwish1,2, Sergey Popov3
1Department of Paediatric Surgery, Noah's Ark Children's Hospital, University Hospital of Wales, Cardiff, UK.
Abstract:
Neuroblastoma metastasizing to the ovary is rare. We report the 10th case and review the scarce literature. A 5-year-old girl with stage M neuroblastoma presented with an upper abdominal and a pelvic mass. Evaluation after induction showed very good tumour response with three remaining localisations: two abdominal and one pelvic. At gross total resection, the pelvic mass appeared to be the enlarged and abnormal right ovary and was removed completely. Pathology showed an ovarian metastasis. On completion of her postoperative treatment, she achieved complete remission. Literature review showed that underdiagnosing of ovarian metastasis in neuroblastoma is very likely.
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