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Updated: Jan 29, 2026

An Effective Mouse Model of Unilateral Renal Ischemia-Reperfusion Injury
Published on: July 15, 2021
Unilateral Renal Agenesis Diagnosed on Early Prenatal Trans-Vaginal Scans
Osnat Zmora1, Ron Beloosesky2, Ayala Gover3
1Department of Pediatric Surgery, Assaf Harofeh Medical Center, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background:
Unilateral renal agenesis is a rare finding. There are no large-scale studies reporting this finding in early pregnancy.
Objectives:
To evaluate the incidence of unilateral renal agenesis (URA) and of associated anomalies diagnosed by early prenatal trans-vaginal sonography.
Methods:
We performed a retrospective chart review of all 59,382 trans-vaginal scans performed at 14-16 weeks gestation by a single operator at different clinics during the period 1994-2013.
Results:
The incidence of URA was 1:1212 (49/59382 cases). Associated anomalies were diagnosed in 22 cases (45%). Renal anomalies were diagnosed in 22.4%. Extra-renal anomalies (with exclusion of a single umbilical artery or nuchal edema as isolated findings) were diagnosed in 24.5%. Ambiguous genitalia were diagnosed in 8.2%.
Conclusions:
URA is a rare finding in early trans-vaginal sonography. Associated anomalies are very common and should be sought.
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