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Published on: May 25, 2020
Penetrating deep sclerectomy in primary open-angle and pseudoexfoliative glaucoma
Vassilios Kozobolis1,2, Eleni Kalogianni1,2, Haris Sideroudi2
1Eye Clinic, University Hospital of Evros, Alexandroupolis, Greece.
Penetrating deep sclerectomy, a novel glaucoma surgery, significantly reduced intraocular pressure and medication dependence over three years. This modified deep sclerectomy offers a safe and effective treatment option for glaucoma patients.
Area of Science:
- Ophthalmology
- Surgical Innovation
- Glaucoma Management
Background:
- Glaucoma requires effective surgical interventions to control intraocular pressure.
- Standard deep sclerectomy is a known glaucoma surgical technique.
- Modifications aim to improve surgical outcomes and patient management.
Purpose of the Study:
- To evaluate the efficacy and safety of penetrating deep sclerectomy, a modified deep sclerectomy technique.
- To assess the long-term outcomes of this novel antiglaucoma surgical method.
Main Methods:
- Prospective study of 29 patients with medically uncontrolled primary open-angle or pseudoexfoliative glaucoma.
- Fornix-based penetrating deep sclerectomy (deep sclerectomy plus trabeculectomy) with intraoperative mitomycin C.
- 3-year follow-up with regular ocular examinations.
Main Results:
- Average intraocular pressure reduction of 11.24 mmHg (57.88%) over 3 years.
- Complete and qualified success rates of 58.6% and 75.86%, respectively.
- Mean medication use decreased from 3.75 to 0.89, with low complications.
Conclusions:
- Penetrating deep sclerectomy demonstrates very positive outcomes over a 3-year follow-up.
- The addition of controlled trabeculo-Descemet's membrane perforation enhances surgical success.
- This technique appears safe and effective for glaucoma treatment without increased complications.
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