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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Personality Disorders: Dependent and Obsessive-Compulsive01:24

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Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
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Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
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Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

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Statements of the Second Law of Thermodynamics01:15

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The second law of thermodynamics can be stated in several different ways, and all of them can be shown to imply the others. The Clausius’ statement of the second law of thermodynamics is based on the irreversibility of spontaneous heat flow. It states that heat will not flow from the colder body to the hotter body unless some other process is involved. Additionally, as per the Kelvin’s statement, it is impossible to convert the heat from a single source into work without any other...
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Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
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Related Experiment Video

Updated: Jan 29, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Early intervention for obsessive compulsive disorder: An expert consensus statement.

Naomi A Fineberg1, Bernardo Dell'Osso2, Umberto Albert3

  • 1Hertfordshire Partnership University NHS Foundation Trust, Rosanne House, Welwyn Garden City, Hertfordshire AL8 6HG, UK; Center for Clinical & Health Research Services, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK; School of Clinical Medicine, University of Cambridge, Cambridge, UK.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
|February 19, 2019
PubMed
Summary
This summary is machine-generated.

Early intervention is crucial for obsessive-compulsive disorder (OCD) to reduce suffering and disability. Addressing the long duration of untreated illness (DUI) can improve outcomes for individuals with OCD.

Keywords:
CompulsiveDuration of untreated illnessEarly interventionOCDObsessiveStaging

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Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Obsessive-compulsive disorder (OCD) is a prevalent, chronic condition with significant impairment.
  • A high duration of untreated illness (DUI), averaging 10 years in adults, leads to substantial suffering.
  • Effective treatments exist, yet delayed intervention remains a global challenge.

Purpose of the Study:

  • To highlight the negative impact of delayed treatment in OCD.
  • To advocate for early clinical intervention in obsessive-compulsive related disorders.
  • To propose new clinical staging models for OCD prevention.

Main Methods:

  • Consensus statement from international experts (clinicians, neuroscientists).
  • Review of epidemiological, clinical, health economic, and neuroimaging studies.
  • Exploration of brain-based mechanisms of extended DUI.

Main Results:

  • Extended DUI negatively impacts clinical outcomes in OCD.
  • Early intervention is beneficial, similar to other disorders like psychosis.
  • Parallels are drawn with internet-related impulsive-compulsive disorders.

Conclusions:

  • There is a global unmet need for early intervention services for OCD.
  • Early intervention can reduce suffering and disability associated with under-treatment.
  • New clinical staging models are proposed for OCD prevention (primary, secondary, tertiary).