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Updated: Jan 29, 2026

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
Published on: January 22, 2013
Gross handling of pulmonary resection specimen: maintaining the 3-dimensional orientation
Teodora Radonic1, Chris Dickhoff2,3, Mari Mino-Kenudson4
1Department of Pathology Amsterdam University Medical Centers, VU University Medical Center, De Boelelaan 1117, Amsterdam, The Netherlands.
Abstract:
There is limited literature on the gross handling of lung resection specimens. Microscopic examination of the specimen, TNM staging and predictive biomarker testing are fully dependent on an adequate gross handling. In this paper, we present a 3-dimensional (3D) grossing method of oncological lung resection specimens, which ensures proper fixation of the tumor tissue, but also enables accurate correlation with the pre-surgical imaging.
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