Related Experiment Video
Updated: Jan 29, 2026

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
Published on: March 24, 2023
Periarticular Injection Technique to Enhance Pain Relief After Knee Arthroplasty
1Towson Orthopaedic Associates, 8322 Bellona Avenue, Suite 100, Towson, MD 21204.
Introduction:
Currently, a popular form of pain control following total knee arthroplasty is the use of periarticular injections; how the medications are injected is a critical step in the efficacy of this modality.
Step 1 Setup:
The setup includes the injection fluid and two control syringes with a 22-gauge needle.
Step 2 Inject The Lateral Femoral Periosteum:
Inject around the femur before placing the implants.
Step 3 Inject The Posterior Aspect Of The Capsule:
This is another area of rich innervation that needs to be injected carefully.
Step 4 Inject The Medial Periosteum:
Use a similar technique of slow small-volume injections, watching for the periosteal wheal or elevation off the bone.
Step 5 Inject The Capsule And Skin:
Include the lateral gutter and proximal extensor mechanism as well as around the patella, with minimal injection into the skin.
Results:
Careful injection technique improves the outcome of periarticular injections for pain control. Indications ContraindicationsPitfalls & Challenges.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Pain
Self-Evaluation: Self-Enhancement and Self-Verification
Bioavailability Enhancement: Drug Solubility Enhancement
Bioavailability Enhancement: Drug Permeability Enhancement
Analgesia and Pain Management

