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Updated: Jan 29, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Optical coherence tomography angiography for the anterior segment
Wen Di Lee1, Kavya Devarajan1, Jacqueline Chua1,2
11Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Optical coherence tomography angiography (OCTA) is a promising non-invasive eye imaging technique. This review explores anterior segment OCTA (AS-OCTA) developments and challenges for improved ocular diagnostics.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique for ocular vasculature.
- OCTA provides high-resolution, depth-resolved images, making it suitable for anterior segment applications.
- Current OCTA systems are optimized for the posterior segment, posing challenges for anterior segment imaging.
Purpose of the Study:
- To review recent developments and clinical applications of anterior segment OCTA (AS-OCTA).
- To compare commercially available AS-OCTA systems.
- To discuss limitations and propose future directions for AS-OCTA technology.
Main Methods:
- Review of current literature on AS-OCTA.
- Comparison of existing commercial OCTA systems for anterior segment use.
- Analysis of challenges and limitations in adapting OCTA for the anterior segment.
Main Results:
- AS-OCTA has shown promise for imaging the cornea, iris, sclera, and conjunctiva.
- Several challenges exist in adapting posterior segment OCTA technology for anterior segment imaging.
- AS-OCTA offers potential for diagnosing corneal and iris pathologies and surgical planning.
Conclusions:
- AS-OCTA is a developing technology with significant potential for anterior segment eye imaging.
- Further advancements are needed to overcome current limitations and enhance clinical utility.
- AS-OCTA may become a common diagnostic tool in ophthalmology clinics in the future.
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