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Updated: Jan 29, 2026

Modeling Fetal Alcohol Spectrum Disorders in Zebrafish to Characterize the Impact of an Adverse Embryonic Environment on Adult Social Behavior
Published on: February 9, 2024
[Fetal alcohol spectrum disorder. An underdiagnosed neuro-development disorder of uncertain prognosis]
Anna Sans-Fitó1, Anna Solerdelcoll1, Cristina Boix-Lluch2
1Unidad de Neurodesarrollo y Aprendizaje. Hospitales Universitarios Sagrat Cor y General de Cataluña, Barcelona, España.
Abstract:
Prenatal exposure to alcohol is the cause of cognitive and behavioural disorders grouped under the term fetal alcohol spectrum disorders (FASD). The long-term evolution of subjects with FASD is often unfavourable, especially in social and academic fields. Executive dysfunction is a hallmark deficit for children with FASD with increased rates of externalizing behaviours, such as aggressiveness and frequently delinquency in adolescence and adulthood. Deficits in social skills, empathy and communication ability are frequent observed among FASD. Prenatal exposure to alcohol is the most frequent cause of acquired and preventable neurodevelopmental disorder.
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