[Treatment of attention-deficit/hyperactivity disorder in clinical practice. A retrospective study]

Ana López-López1, María Luisa Poch-Olivé2, Javier López-Pisón3

  • 1Departamento de Psicología, Hospital Son Llatzer, Son Ferriol, Islas Baleares, España.

Medicina
|February 19, 2019
PubMed

Insights

Methylphenidate, particularly immediate-release formulations, is the primary pharmacological treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children. Early treatment onset significantly impacts therapeutic outcomes.

Area of Science:

  • Neuroscience
  • Pediatric Psychiatry
  • Pharmacology

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent, chronic neurodevelopmental disorder with complex genetic and environmental influences.
  • ADHD often presents with comorbid conditions, affecting a significant majority of diagnosed children.
  • Understanding therapeutic management patterns is crucial for optimizing ADHD care.

Purpose of the Study:

  • To retrospectively analyze the therapeutic management strategies employed in children diagnosed with ADHD.
  • To identify the most common pharmacological treatments and factors influencing treatment choices.
  • To investigate the relationship between treatment type, patient demographics, and treatment outcomes.

Main Methods:

  • Retrospective analytical study design.
  • Inclusion of a sample of 82 children diagnosed with ADHD.
  • Analysis of treatment modalities, including pharmacological interventions (methylphenidate, atomoxetine) and their formulations.

Main Results:

  • Pharmacological treatment was the predominant therapeutic approach (90.2%).
  • Methylphenidate, in both immediate-release (46.0%) and sustained-release (51.4%) formulations, was the most frequently prescribed medication.
  • Atomoxetine use was minimal (2.7%), and treatment abandonment occurred in 20.3% of patients. A significant correlation was observed between the age of treatment onset and outcomes, unlike gender or ADHD subtype.

Conclusions:

  • Pharmacological treatment, especially methylphenidate, remains the cornerstone of ADHD management in this pediatric cohort.
  • The low utilization of non-stimulant alternatives like atomoxetine warrants further investigation.
  • Early initiation of ADHD treatment is a critical factor influencing therapeutic success.

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