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Updated: Jan 29, 2026
Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
Published on: December 13, 2024
Fabrication of dual network self-healing alginate/guar gum hydrogels based on polydopamine-type microcapsules from
Zhilu Rao1, Shumin Liu1, Ruiyue Wu1
1School of Chemistry and Materials Science, Ludong University, Key Laboratory of High Performance and Functional Polymer in the Universities of Shandong Province, Collaborative Innovation Center of Shandong Province for High Performance Fibers and Their Composites, Yantai, China.
Abstract:
In this manuscript, dual network self-healing alginate/guar gum hydrogels with polydopamine-type microcapsules from mesoporous silica nanoparticles were facilely prepared through one-pot method. Glutaraldehyde (GA) was used as a crosslinking agent to crosslink guar gum and sodium alginate, respectively. Metal-ligand interactions as reversible non-covalent bonds make the dual network hydrogels have a high degree of self-healing ability, which FeCl3·6H2O was coordinated with sodium alginate and polydopamine on the surface of microcapsules, respectively. The dual network structure significantly enhances the strength of the hydrogels (up to 7.3 MPa). It has also proved that these hydrogels exhibit excellent self-healing performance at ambient temperatures, which self-healing efficiency can reach to 95.5%. The obtained self-healing hydrogels have a promising application prospect for the design and synthesis of functional self-healing materials.
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