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Updated: Jan 29, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Shedding of methicillin-resistant Staphylococcus aureus by colonized patients during procedures and patient care
Heba Alhmidi1, Jennifer L Cadnum1, Sreelatha Koganti1
1Research Service, Louis Stokes Veterans Affairs Medical Center,Cleveland, Ohio.
Objective:
Medical procedures and patient care activities may facilitate environmental dissemination of healthcare-associated pathogens such as methicillin-resistant Staphylococcus aureus (MRSA).
Design:
Observational cohort study of MRSA-colonized patients to determine the frequency of and risk factors for environmental shedding of MRSA during procedures and care activities in carriers with positive nares and/or wound cultures. Bivariate analyses were performed to identify factors associated with environmental shedding.
Setting:
A Veterans Affairs hospital.
Participants:
This study included 75 patients in contact precautions for MRSA colonization or infection.
Results:
Of 75 patients in contact precautions for MRSA, 55 (73%) had MRSA in nares and/or wounds and 25 (33%) had positive skin cultures. For the 52 patients with MRSA in nares and/or wounds and at least 1 observed procedure, environmental shedding of MRSA occurred more frequently during procedures and care activities than in the absence of a procedure (59 of 138, 43% vs 8 of 83, 10%; P 0.9 m from the patient (52 of 138, 38% vs 25 of 138, 18%; P = .0004). Contamination occurred frequently on surfaces touched by personnel (12 of 38, 32%) and on portable equipment used for procedures (25 of 101, 25%). By bivariate analysis, the presence of a wound with MRSA was associated with shedding (17 of 29, 59% versus 6 of 23, 26%; P = .04).
Conclusions:
Environmental shedding of MRSA occurs frequently during medical procedures and patient care activities. There is a need for effective strategies to disinfect surfaces and equipment after procedures.
Insights
Healthcare procedures can spread methicillin-resistant Staphylococcus aureus (MRSA). Environmental shedding of MRSA is common during patient care, especially from wounds, highlighting the need for better disinfection strategies.
Area of Science:
- Infectious Diseases
- Healthcare Epidemiology
- Microbiology
Background:
- Healthcare-associated pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA), can spread through environmental contamination during medical procedures.
- Understanding the dynamics of MRSA environmental dissemination is crucial for infection control in healthcare settings.
Purpose of the Study:
- To determine the frequency of environmental shedding of MRSA by colonized patients during medical procedures and care activities.
- To identify risk factors associated with MRSA environmental shedding in a healthcare environment.
Main Methods:
- An observational cohort study was conducted with 75 patients under contact precautions for MRSA.
- Environmental samples were collected during and after procedures and care activities.
- Bivariate analyses were used to identify factors associated with MRSA shedding.
Main Results:
- Environmental shedding of MRSA occurred in 43% of observed procedures, significantly more than during non-procedural care (10%).
- MRSA was frequently detected on surfaces near the patient (38%) and on portable equipment (25%).
- The presence of an MRSA-positive wound was significantly associated with environmental shedding (59% vs. 26%).
Conclusions:
- Environmental shedding of MRSA is a frequent occurrence during routine medical procedures and patient care.
- Effective strategies for disinfecting surfaces and equipment after patient interactions are necessary to mitigate MRSA transmission.
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