Related Experiment Video
Updated: Jan 29, 2026

Subjective Refraction Test Using a Smartphone for Vision Screening
Published on: October 18, 2024
Curious case of retrolental mass: An unusual tele-screening artifact
Ratnesh Ranjan1, Parag K Shah1, Venkatapathy Narendran1
1Department of Paediatric Retina and Ocular Oncology, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India.
Insights
A case of retinopathy of prematurity (ROP) tele-screening revealed an imaging artifact mimicking a serious eye condition. This false-positive finding highlights the importance of careful interpretation in ROP diagnostics.
Area of Science:
- Ophthalmology
- Medical Imaging
- Neonatology
Background:
- Premature infants require regular screening for retinopathy of prematurity (ROP).
- Tele-screening utilizes advanced imaging systems for remote ROP assessment.
- High-quality imaging and trained staff are crucial for accurate ROP diagnosis.
Observation:
- An anterior segment image from ROP tele-screening showed a retrolental mass lesion.
- The lesion in the right eye resembled retinoblastoma or medulloepithelioma.
- The infant was referred for further evaluation due to the concerning imaging finding.
Findings:
- A detailed examination at the base hospital revealed no retrolental lesion or intraocular mass.
- The observed lesion was identified as an imaging artifact.
- This artifact occurred despite the use of a high-quality imaging system and trained personnel.
Implications:
- Imaging artifacts can lead to false-positive referrals in ROP tele-screening.
- Careful interpretation of imaging is essential to avoid unnecessary patient anxiety and interventions.
- This case underscores the need for vigilance in diagnostic imaging, even with advanced technology.
Abstract:
We are presenting a case of premature baby born at 32 weeks of gestation who was under regular follow-up with our retinopathy of prematurity (ROP) tele-screening team. During final follow-up at 41 weeks of postconceptional age, anterior segment image captured with RetCam showed a retrolental mass lesion in right eye resembling retinoblastoma or medulloepithelioma. The baby was referred to our base hospital for further evaluation, where a detailed examination showed no retrolental lesion or intraocular mass. This is the first case where imaging artifact, despite use of high-quality imaging system by well-trained staff, during ROP tele-screening appeared like a retrolental mass lesion and resulted in false-positive referral.
More Related Videos
09:04Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow
Published on: April 18, 2019
08:19Protocol for the Evaluation of MRI Artifacts Caused by Metal Implants to Assess the Suitability of Implants and the Vulnerability of Pulse Sequences
Published on: May 17, 2018
Related Concept Videos
Unusual Results
According to the range rule of thumb, any value above or below two standard deviations, 2σ from the mean, μ is considered unusual.
Maximum unusual value =...
z Scores and Unusual Values
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
Atomic Mass
Molar Mass
Formula Mass and Mole Concepts of Compounds
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...