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Does Coronary Reimplantation After Neoaortic Reconstruction Increase Aortic Regurgitation?
Kwang Ho Choi1, Si Chan Sung2, Hyungtae Kim1
1Department of Thoracic and Cardiovascular Surgery, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Mulgeum-eup, Yangsan, Gyeongsangnam, 50612, Republic of Korea.
Insights
Coronary reimplantation after neoaortic reconstruction (CRANR) in arterial switch operation (ASO) does not increase aortic regurgitation (AR). This study found similar rates of early and late AR between CRANR and open coronary reimplantation techniques.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Arterial switch operation (ASO) is a standard procedure for d-transposition of the great arteries.
- Coronary reimplantation after neoaortic reconstruction (CRANR) facilitates coronary transfer but may risk aortic valve injury.
- Aortic regurgitation (AR) is a potential complication following ASO.
Purpose of the Study:
- To determine if the CRANR technique increases the incidence of postoperative AR compared to open coronary reimplantation (OCR).
Main Methods:
- Retrospective review of 176 patients who underwent ASO between March 1994 and August 2017.
- Patients were divided into two groups: CRANR (n=138) and OCR (n=38).
- Incidences of early and late postoperative AR were compared, defining mild or greater AR as significant AR.
Main Results:
- No significant difference in the incidence of early postoperative AR at discharge between CRANR (16.6%) and OCR (21.1%) groups (p=0.53).
- No significant difference in freedom from significant AR at 5 years between CRANR (62.4%) and OCR (59.9%) groups (p=0.73).
- Only one patient in the CRANR group developed moderate AR, with no surgical intervention required for the aortic valve in either group.
Conclusions:
- The CRANR technique in ASO does not increase the incidence of early or late postoperative aortic regurgitation.
- CRANR is a safe alternative for coronary transfer during ASO with comparable AR rates to OCR.
Abstract:
Coronary reimplantation after neoaortic reconstruction (CRANR) in the arterial switch operation (ASO) allows easy selection of accurate coronary transfer sites in the distended neoaorta. However, neoaortic valve injury may occur during coronary reimplantation. We determined whether the CRANR procedure increased the incidence of aortic valve regurgitation (AR) after ASO. Between March 1994 and August 2017, 227 patients underwent ASO. Since September 2000 CRANR has been performed on 155 patients and open coronary reimplantation (OCR) on 72. Patients who had undergone aortocoronary flaps procedures (n = 13), had early or late mortality (n = 27), or lacked data (n = 11) were excluded. We enrolled and retrospectively reviewed the medical records of 176 patients who were followed up for postoperative AR: 38 underwent OCR and 138 underwent CRANR. We compared the incidences of early and late postoperative AR in both groups. We defined mild or greater AR as "significant AR." The groups did not differ in body weight at operation, great artery relationship, and coronary artery anatomy. The incidences of significant AR at discharge were 21.1% (8/38) in the OCR group and 16.6% (23/138) in the CRANR group (p = 0.53). The freedom from significant AR at 5 years was 59.9% in the OCR group and 62.4% in the CRANR group with no difference between the two groups (p = 0.73). Moderate AR occurred in one patient in the CRANR group. No surgical intervention was required for the aortic valve in either group. ASO using the CRANR technique did not increase the incidence of postoperative early and late AR.
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