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Related Concept Videos

Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

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Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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B Vitamins and Ageing.

Kathleen Mikkelsen1, Vasso Apostolopoulos2

  • 1Institute for Health and Sport, Victoria University, Werribee, VIC, Australia.

Sub-Cellular Biochemistry
|February 20, 2019
PubMed
Summary
This summary is machine-generated.

Maintaining adequate vitamin B levels is crucial for overall health, especially in older adults. Optimizing vitamin B status may help prevent age-related diseases like cardiovascular disease and cognitive decline.

Keywords:
AgeingCobalaminFolateNiacinPyridoxineRiboflavinThiamineVitamin B

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Area of Science:

  • Nutrition science
  • Gerontology
  • Biochemistry

Background:

  • Vitamin B complex is essential for numerous physiological processes, including energy metabolism, DNA repair, and immune function.
  • Deficiencies in B vitamins are associated with various health issues, such as neurocognitive and immune dysfunction.
  • In elderly populations, B vitamin deficiency is linked to increased risks of cardiovascular disorders, cognitive decline, osteoporosis, and degenerative diseases.

Purpose of the Study:

  • To broadly discuss the role of B vitamins in the ageing process.
  • To highlight the importance of optimizing B vitamin status in the elderly.
  • To explore the potential of B vitamins in preventing age-related degenerative diseases.

Main Methods:

  • Literature review and synthesis of existing research on B vitamins and ageing.
  • Analysis of the impact of B vitamin deficiency on age-related health conditions.
  • Discussion of the benefits of maintaining adequate B vitamin levels in older adults.

Main Results:

  • B vitamins play a vital role in maintaining health and preventing disease across the lifespan.
  • Ageing is associated with an increased risk of B vitamin deficiency, exacerbating age-related health problems.
  • Adequate B vitamin status in the elderly is crucial for mitigating risks of cardiovascular disease, cognitive dysfunction, and osteoporosis.

Conclusions:

  • Optimizing B vitamin status in the elderly is a promising strategy for the prevention of degenerative diseases.
  • Maintaining sufficient B vitamin levels supports healthy ageing and overall wellbeing in older adults.
  • Further research into targeted B vitamin supplementation may be beneficial for geriatric health.