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Types of Hormones

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Related Experiment Video

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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

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Published on: January 19, 2024

Melasma: How hormones can modulate skin pigmentation.

Angela Filoni¹, Maria Mariano¹, Norma Cameli¹

¹San Gallicano Dermatological Institute (IRCCS), Rome, Italy.

Journal of Cosmetic Dermatology

|February 20, 2019

Summary

Melasma development is linked to genetics and sun exposure, but hormonal factors like pregnancy and therapies also play a role. The precise link between hormone secretion and melasma remains complex and requires further investigation.

Keywords:

hormones melasma pigmentation

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Area of Science:

Dermatology
Endocrinology

Background:

Melasma is a common skin condition influenced by genetic predisposition and sunlight.
Hormonal factors, including pregnancy, hormone therapies, and oral contraceptives, are frequently associated with melasma.
Limited laboratory studies exist on the correlation between hormonal alterations and melasma.

Purpose of the Study:

To review existing literature on hormonal variations in individuals with melasma.
To explore the complex relationship between hormone secretion and melasma development.
To present clinical cases illustrating the challenges in defining this association.

Main Methods:

Literature review of studies on hormone variations in men and women with melasma.
Analysis of clinical case reports.

Main Results:

Hormonal alterations are frequently reported in association with melasma.
Data on laboratory correlations between hormones and melasma are limited.
Clinical cases highlight the difficulty in definitively defining the hormone-melasma relationship.

Conclusions:

While hormonal factors are implicated in melasma, the precise biochemical and physiological links are not fully understood.
Further research, including robust laboratory analyses, is needed to clarify the role of hormone secretion in melasma pathogenesis.
The interplay between genetics, environment, and hormones in melasma requires continued investigation.