Related Experiment Video
Updated: Jan 29, 2026

Analyzing Platelet Subpopulations by Multi-color Flow Cytometry
Published on: June 10, 2025
Platelet Flow Cytometry: Instrument Setup, Controls, and Panel Performance
Benjamin E J Spurgeon1, Khalid M Naseem1
1Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Abstract:
Platelet flow cytometry is widely used in cardiovascular medicine as the platelet surface is rich in clinical biomarkers. Surface profiling is critical in disease management, but current assays can abet clinical errors as they are suboptimal and prone to bias. Accordingly, the technical and analytical advances that can be used to create high quality assays with minimal error and maximal sensitivity were reviewed. Specifically, the best practices for instrument setup, quality control, panel design, titration, gating, and compensation were described. Adherence to these practices will enhance the validity and reliability of platelet flow cytometry in clinical/research settings. © 2019 International Clinical Cytometry Society.
Related Concept Videos
High-Performance Liquid Chromatography: Instrumentation
Flow Cytometry
In...
Control of Power Flow
Wood Panel Products
Instrument Calibration
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Instrumentation Amplifier
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...

