Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

314
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
314
Venous Return01:04

Venous Return

12.2K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.2K
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

433
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
433
Behavior of Concrete Under Compressive Load01:23

Behavior of Concrete Under Compressive Load

623
Concrete exhibits specific behaviors under different compressive loads. Understanding this is crucial for understanding its structural integrity. When concrete undergoes uniaxial compression, it tends to develop cracks that run parallel to the direction of the force. These parallel cracks stem from localized tensile stresses that occur perpendicular to the compression direction. Additionally, angled cracks may appear due to the formation of shear planes.
As the concrete specimen fractures under...
623
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

251
Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
251
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

307
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
307

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinicians' Knowledge, Confidence and Skills: A Retrospective Evaluation of an Interdisciplinary Extracorporeal Membrane Oxygenation Simulation Workshop.

Nursing in critical care·2026
Same author

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE): A Protocol for a Pre-Planned Sub-Study of a Randomized Clinical Trial.

Acta anaesthesiologica Scandinavica·2026
Same author

Long-Term Outcomes From a Decade of Donation After Circulatory Death Heart Transplantation in Australia.

JACC. Heart failure·2026
Same author

Preferences for Blood Glucose Management in Adult Intensive Care Unit Patients-An International Survey.

Acta anaesthesiologica Scandinavica·2026
Same author

Clinical Outcomes and Safety Profile of Tranexamic Acid Use in Critically Ill Patients with Bleeding: A Single-Center Retrospective Descriptive Study.

Healthcare (Basel, Switzerland)·2026
Same author

Dexmedetomidine for sedation during noninvasive ventilation in COVID-19 patients from the Helmet-COVID randomized clinical trial post-hoc analysis.

Scientific reports·2026

Related Experiment Video

Updated: Jan 29, 2026

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
13:27

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia

Published on: May 6, 2014

49.0K

Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis.

Yaseen M Arabi1, Fahad Al-Hameed1, Karen E A Burns1

  • 1From the College of Medicine, King Saud Bin Abdulaziz University for Health Sciences (Y.M.A., S.J.A., S.A.I.A., A.A.-D.), the Departments of Intensive Care (Y.M.A., S.J.A., S.A.I.A., A.A.-D.) and Emergency Medicine, (S.J.A.), Ministry of National Guard Health Affairs, Military Medical Services, Ministry of Defense (Y. Mandourah), the Department of Intensive Care Services, Prince Sultan Military Medical City (G.A.A.), the Department of Pulmonary and Critical Care Medicine, King Fahad Medical City (M.A., H.L.), Critical Care Medicine Department, King Faisal Specialist Hospital and Research Center (H.H.), and the Department of Biostatistics and Bioinformatics (J.J.) and Research Office (L.Y.A.), King Abdullah International Medical Research Center (Y.M.A., S.J.A., S.A.I.A., A.A.-D.), Riyadh, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, and the Intensive Care Department, Ministry of National Guard Health Affairs (F.A.-H.), and Critical Care Section, Department of Medicine, King Faisal Specialist Hospital and Research Center (I.K.), Jeddah, the Department of Emergency and Critical Care Medicine, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University (M.S.A.), Dammam, the Department of Critical Care Medicine, King Khalid University, Asir Central Hospital (A.A.B.), Abha, and King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, and the Intensive Care Division, Department of Medicine, King Abdulaziz Hospital (A.A.A.), Al Ahsa - all in Saudi Arabia; St. Michael's Hospital, Li Ka Shing Knowledge Institute (K.E.A.B.), the Department of Medicine, Sinai Health System (S.M.), and Interdepartmental Division of Critical Care Medicine, University of Toronto (K.E.A.B, S.M.) - all in Toronto; the George Institute for Global Health (S.F.), the Department of Intensive Care Medicine, Centre for Applied Medical Research, St. Vincent's Hospital (H.B.), and the University of New South Wales, Sydney (S.F., H.B.), and Intensive Care Department, Gosford Hospital, Gosford, NSW (A.G.) - all in Australia; and the Department of Anesthesiology and Critical Care, King George's Medical University, Lucknow (Z.A.), and Institute of Critical Care and Anesthesiology, Medanta-The Medicity, Gurgaon (Y. Mehta) - both in India.

The New England Journal of Medicine
|February 20, 2019
PubMed
Summary

Adjunctive intermittent pneumatic compression did not significantly lower deep-vein thrombosis rates in critically ill patients already receiving pharmacologic thromboprophylaxis. This study found no added benefit for preventing blood clots with compression devices in this high-risk group.

More Related Videos

A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression
07:23

A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression

Published on: September 13, 2019

7.1K
Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms
05:15

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms

Published on: January 10, 2025

1.7K

Related Experiment Videos

Last Updated: Jan 29, 2026

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
13:27

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia

Published on: May 6, 2014

49.0K
A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression
07:23

A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression

Published on: September 13, 2019

7.1K
Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms
05:15

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms

Published on: January 10, 2025

1.7K

Area of Science:

  • Critical Care Medicine
  • Vascular Surgery
  • Hematology

Background:

  • Critically ill patients are at high risk for deep-vein thrombosis (DVT).
  • Pharmacologic thromboprophylaxis is standard, but its effectiveness may be enhanced.
  • The role of intermittent pneumatic compression (IPC) as an adjunctive therapy is uncertain.

Purpose of the Study:

  • To determine if intermittent pneumatic compression (IPC) reduces DVT incidence in critically ill patients receiving pharmacologic thromboprophylaxis.
  • To compare DVT rates between patients receiving IPC plus pharmacologic prophylaxis and those receiving pharmacologic prophylaxis alone.

Main Methods:

  • Randomized controlled trial involving 2003 critically ill adult patients.
  • Intervention group received IPC (≥18 hours/day) plus pharmacologic thromboprophylaxis.
  • Control group received pharmacologic thromboprophylaxis alone.
  • Primary outcome: proximal lower-limb DVT detected by ultrasonography.

Main Results:

  • The incidence of proximal lower-limb DVT was 3.9% in the IPC group and 4.2% in the control group (Relative Risk: 0.93; 95% CI: 0.60-1.44).
  • No significant difference in DVT rates between the groups.
  • Overall venous thromboembolism and 90-day mortality rates were also similar between groups.

Conclusions:

  • Adjunctive IPC did not significantly reduce the incidence of proximal lower-limb DVT in critically ill patients receiving pharmacologic thromboprophylaxis.
  • Current evidence does not support routine use of IPC in this patient population.
  • Further research may explore specific subgroups or alternative DVT prevention strategies.