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Updated: Jan 29, 2026

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Chronic Rhinosinusitis: Does Allergy Play a Role?
Sonya Marcus1, John M DelGaudio2, Lauren T Roland3
1Department of Otolaryngology-Head and Neck Surgery, Emory University, Atlanta, GA 30308, USA. sonya.marcus@emory.edu.
Abstract:
A few chronic rhinosinusitis (CRS) variants have demonstrated a strong association with environmental allergy, including allergic fungal rhinosinusitis (AFRS) and central compartment atopic disease (CCAD). However, the overall relationship between CRS and allergy remains poorly defined. The goal of this review is to evaluate the relationship between CRS and allergy with a focus on specific CRS variants.
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