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Related Experiment Video

Updated: Jan 28, 2026

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Different suturing techniques in thoracic incision: protocol for a feasibility randomised controlled trial.

Zonghui Liu1,2, Xiangyu Liu1, Lin He1

  • 1Department of Aesthetic, Plastic and Maxillofacial Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

BMJ Open
|February 21, 2019
PubMed
Summary

This study assesses the feasibility of a randomized controlled trial comparing two skin closure techniques: wedge-shaped excision and modified buried vertical mattress suture (WE-MBVMS) versus buried intradermal suture (BIS) for thoracic incisions. Findings will guide a larger trial on scar cosmetic outcomes.

Keywords:
buried intradermal suturecosmesiseversionmodified buried vertical mattress suturescar evaluation

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Area of Science:

  • Surgical Innovation
  • Plastic Surgery
  • Clinical Trials

Background:

  • The wedge-shaped excision and modified buried vertical mattress suture (WE-MBVMS) technique shows promise for ideal skin closure.
  • Clinical evidence comparing WE-MBVMS to other methods, like buried intradermal suture (BIS), is limited.
  • Thoracic incisions, especially those involving costal cartilage harvesting, require optimal wound closure for cosmetic results.

Purpose of the Study:

  • To establish the feasibility of a randomized controlled trial (RCT) comparing WE-MBVMS and BIS for thoracic incision closure.
  • To evaluate recruitment rates, participant retention, and intervention times for a future definitive RCT.
  • To collect preliminary data on cosmetic scar outcomes to inform sample size calculations for a fully powered study.

Main Methods:

  • A feasibility RCT involving 78 participants undergoing surgery for costal cartilage harvesting.
  • Randomization of participants in a 1:1 ratio to either WE-MBVMS or BIS.
  • Assessment of trial feasibility through metrics including eligibility, recruitment, withdrawal, retention, and follow-up rates at 3, 6, and 12 months.

Main Results:

  • Feasibility data collection is ongoing.
  • Preliminary cosmetic scar data will be gathered to inform future study design.
  • The study aims to determine the viability of a large-scale RCT comparing these two suture techniques.

Conclusions:

  • This feasibility study is crucial for designing a robust, fully powered RCT.
  • The results will provide essential information on the comparative effectiveness and cosmetic outcomes of WE-MBVMS versus BIS.
  • Successful completion will pave the way for evidence-based recommendations on skin closure techniques in thoracic surgery.