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Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
Priyanka Michael1, Espen Hansen1, Johan Isaksson2
1Marbio UiT-The Arctic University of Norway, Breivika, Tromsø, Norway.
Abstract:
The new guanidine alkaloid Dendrobeaniamine A (1) was isolated from the organic extract of the Arctic marine bryozoan Dendrobeania murrayana. The chemical structure of 1 was elucidated by spectroscopic experiments, including 1D and 2D NMR and HRESIMS analysis. Compound 1 is a lipoamino acid, consisting of a C12 fatty acid anchored to the amino acid arginine. The bioactivity of 1 was evaluated using cellular and biochemical assays, but the compound did not show cytotoxic, antimicrobial, anti-inflammatory or antioxidant activities.
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