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Updated: Jan 28, 2026

Ultrasound Assessment of Endothelial Function: A Technical Guideline of the Flow-mediated Dilation Test
Published on: April 27, 2016
No. 375-Clinical Practice Guideline on the Use of First Trimester Ultrasound
Michiel C Van den Hof1, Mila Smithies2, Ori Nevo3
1Halifax, NS.
Objective:
This guideline reviews the clinical indications for first trimester ultrasound.
Outcome:
Proven clinical benefit has been reported from first trimester ultrasound.
Evidence:
A Medline search and bibliography reviews in relevant literature provided the evidence.
Values:
Content and recommendations were reviewed by the principal authors and the Diagnostic Imaging Committee of the Society of Obstetricians and Gynaecologists of Canada. Levels of evidence were judged as outlined by the Canadian Task Force on Preventive Health Care.
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