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Related Concept Videos

Septins01:19

Septins

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Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. In 1971 while studying the cell division cycle in mutant Saccharomyces cerevisiae Harwell et al. first identified the septin-related genes playing a crucial role in yeast cytokinesis. Fluorescence microscopy revealed that these proteins localize at the budding neck as rings. These ring-like proteins were then named Septins by John Pringle, and...
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Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
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Role of Septins01:02

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Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
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Yeast Signaling01:28

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Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
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The psychodynamic perspective in psychology asserts that most personality functions operate unconsciously, outside of awareness. This means that the motives and emotions driving behavior often remain hidden, automatically buried in the unconscious mind as a defense mechanism to shield us from psychological distress. According to this theory, the unconscious mind contains thoughts, memories, and emotions that are too disturbing to face directly.
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As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
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Related Experiment Video

Updated: Jan 28, 2026

Analysis of the Development of a Morphological Phenotype as a Function of Protein Concentration in Budding Yeast
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Septin functions during neuro-development, a yeast perspective.

Julien Falk1, Leila Boubakar1, Valérie Castellani1

  • 1University of Lyon, University of Lyon 1 Claude Bernard Lyon1, NeuroMyoGene Institute, CNRS UMR5310, INSERM U1217, 8 Avenue Rockefeller, Lyon F-69008, France.

Current Opinion in Neurobiology
|February 21, 2019
PubMed
Summary
This summary is machine-generated.

Septins are crucial for neuron development and function, playing key roles in cell morphology. This review highlights septin functions in neuron differentiation, comparing them to yeast polarity programs.

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Area of Science:

  • Cell Biology
  • Neuroscience
  • Molecular Biology

Background:

  • Septins are conserved protein complexes with essential roles in cell division and morphology across eukaryotes.
  • Initially studied in yeast, septins are now recognized for their diverse functions in mammalian cells, including neuronal development.

Purpose of the Study:

  • To review recent advances in understanding septin-mediated processes during neuron differentiation.
  • To compare and contrast septin functions in neuronal polarity with those in yeast polarity programs.

Main Methods:

  • Literature review of recent research on septins in neurodevelopment.
  • Comparative analysis of septin roles in yeast and neuronal polarity.

Main Results:

  • Septins are critical for the morphological differentiation and compartmentalization of neurons.
  • Septin functions in neurons share similarities with, yet also exhibit differences from, yeast polarity mechanisms.

Conclusions:

  • Septins are key regulators of neuronal structure and function, essential for neurodevelopment.
  • Understanding septin-mediated polarity programs offers insights into both neuronal and yeast cell biology.