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Naphthocage: A Flexible yet Extremely Strong Binder for Singly Charged Organic Cations
Fei Jia1,2, Henrik Hupatz1, Liu-Pan Yang2
1Institut für Chemie und Biochemie , Freie Universität Berlin , Takustrasse 3 , 14195 Berlin , Germany.
Abstract:
We report a quite flexible naphthol-based cage (so-called "naphthocage") which adopts a self-inclusion conformation in its free state and is able to bind singly charged organic cations extremely strongly ( Ka > 107 M-1). Ion-selective electrodes prepared with this naphthocage show a super-Nernstian response to acetylcholine. In addition, the highly stable complex (1010 M-1) between ferrocenium and the naphthocage can be switched electrochemically, which lays a basis for its application in stimuli-responsive materials.
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