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Gastrostomy tubes appear to be safe following pediatric orthotopic heart transplant
Rick D Vavolizza1, David F Grabski2, Daniel E Levin3
1University of Virginia School of Medicine, Charlottesville, Virginia.
Insights
Gastrostomy tube (GT) placement is safe for pediatric patients with heart transplants who are on immunosuppressants. This study found no major complications in these patients, suggesting it
Area of Science:
- Pediatric Surgery
- Cardiology
- Immunology
Background:
- Oral aversion is a common reason for gastrostomy tube (GT) placement in children.
- Congenital heart disease (CHD) patients needing orthotopic heart transplant (OHT) may develop oral aversion.
- The safety of GT placement in immunosuppressed pediatric OHT patients is not well-documented.
Purpose of the Study:
- To evaluate the safety of gastrostomy tube (GT) placement in pediatric patients who have undergone orthotopic heart transplant (OHT).
- To assess the risk of wound site complications in immunosuppressed OHT recipients requiring GT placement.
Main Methods:
- Retrospective case series of pediatric OHT recipients who had GT placement between January 1, 2009, and August 1, 2018.
- Data collected on major GT complications (wound breakdown, infection, leakage, ileus, emesis) and minor complications (granulation tissue).
Main Results:
- Six pediatric OHT patients underwent GT placement during the study period.
- No major GT complications (30-day or 90-day) were observed.
- One patient experienced excessive granulation tissue; no infections or other major adverse events occurred.
Conclusions:
- Gastrostomy tube placement appears safe for pediatric OHT patients on immunosuppressive therapy who have feeding difficulties.
- This study provides initial evidence on the safety profile of GTs in this vulnerable population.
- Findings may assist clinicians in managing feeding support for pediatric OHT recipients.
Background:
Gastrostomy tube (GT) placement is a common pediatric surgical procedure typically indicated for oral aversion. This may develop in patients with congenital heart disease (CHD) who require an orthotopic heart transplant (OHT). The safety profile of GT placement in OHT patients who are immunosuppressed is unknown. Given the potential increased risk of wound site complications on a patient receiving immunosuppression, we sought to determine the safety profile of GT placement in pediatric patients with OHT.
Materials And Methods:
We performed a retrospective case series of all pediatric OHT recipients who subsequently underwent GT placement from January 1, 2009, to August 1, 2018, at the University of Virginia Children's Hospital. Major GT complications of wound breakdown, wound infection, peristomal GT leakage, ileus, or persistent emesis, and minor GT complication including the presence of granulation tissue are reported.
Results:
Six patients who had a pediatric OHT subsequently underwent GT placement over the study period. There were no major 30-day or 90-day GT complications. One patient had excessive granulation tissue at their GT site. There were no accounts of acute kidney injury, urinary tract infection, sepsis, or pneumonia.
Conclusion:
Gastrostomy tube (GT) placement appears to be safe in pediatric OHT patients who are on immunosuppressive medications and unable to feed orally. This is the first study documenting the safety profile of GTs in pediatric OHT patients and may aid clinicians to make decisions regarding this intervention.
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