Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effect of steroids in maxillofacial surgery.

I R Munro1, J B Boyd, D J Wainwright

  • 1Division of Plastic Surgery (Department of Surgery), Hospital for Sick Children, Toronto, Ontario, Canada.

Annals of Plastic Surgery
|November 1, 1986
PubMed
Summary

This study investigated if steroids reduce swelling after jaw surgery in pediatric patients. Results showed no significant difference in facial swelling between patients receiving dexamethasone and those receiving a placebo.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A loss of FUS/TLS function leads to impaired cellular proliferation.

Cell death & disease·2014
Same author

The ugly face: deformity not defectiveness.

Canadian family physician Medecin de famille canadien·2010
Same author

Angular nerve: new insights on innervation of the corrugator supercilii and procerus muscles.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2006
Same author

Repair of a large septal perforation with a radial forearm free flap: brief report of a case.

Ear, nose, & throat journal·2001
Same author

Early treatment of severe mandibular hypoplasia with distraction mesenchymogenesis and bilateral free fibula flaps.

The Journal of craniofacial surgery·2001
Same author

The vascularized pig fibula bone flap model: effect of segmental osteotomies and internal fixation on blood flow.

Plastic and reconstructive surgery·2000

Area of Science:

  • Oral and Maxillofacial Surgery
  • Pediatric Medicine
  • Pharmacology

Background:

  • Maxillofacial surgeries, such as mandibular and maxillary osteotomies, can lead to significant post-operative facial swelling.
  • Surgeons often subjectively believe that steroid administration can mitigate this swelling.
  • Objective evidence is needed to confirm the therapeutic efficacy of steroids in these procedures.

Purpose of the Study:

  • To objectively evaluate the therapeutic effect of dexamethasone in reducing facial swelling after pediatric maxillofacial surgery.
  • To compare key post-operative recovery parameters between patients receiving steroids and those receiving a placebo.

Main Methods:

  • A randomized, double-blind study involving 36 pediatric patients undergoing osteotomies.

Related Experiment Videos

  • Administration of dexamethasone or saline placebo preoperatively and for 48 hours postoperatively.
  • Standardized surgical techniques and fluid management.
  • Objective assessment of facial swelling via photographic comparison by independent observers.
  • Comparison of intubation duration and time to satisfactory oral intake.

    • Main Results:

    • Patients receiving dexamethasone showed a trend towards reduced facial swelling, but the difference was not statistically significant compared to the placebo group.
    • No significant differences were observed in the mean intubation period or the time until satisfactory oral intake between the two groups.
    • The study did not provide objective confirmation of the subjective belief that steroids reduce post-operative facial swelling.

    Conclusions:

    • Dexamethasone administration did not significantly reduce facial swelling following pediatric mandibular and/or maxillary osteotomies in this study.
    • The findings do not support the routine use of steroids for reducing post-operative swelling in this patient population.
    • Further research may be warranted to explore potential benefits in specific subgroups or with different steroid regimens.