Related Experiment Video
Updated: Jan 28, 2026
07:28
TChIP-Seq: Cell-Type-Specific Epigenome Profiling
Published on: January 23, 2019
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Publisher Correction: An evolutionary framework for measuring epigenomic information and estimating
Brad Gulko1,2, Adam Siepel3
1Graduate Field of Computer Science, Cornell University, Ithaca, NY, USA.
Nature Genetics
|February 22, 2019
Summary
A correction was issued for an error in the INSIGHT tool
Area of Science:
- Biostatistics
- Computational Biology
Background:
- The INSIGHT tool is used for measuring entropy.
- Accurate statistical analysis is crucial in computational biology.
Purpose of the Study:
- To correct a previously published error in the INSIGHT tool's methodology.
- To ensure the accuracy of entropy measurements.
Main Methods:
- The error was identified in the 'Statistics and data analysis' section, specifically in the 'Measuring entropy with INSIGHT' subsection.
- The incorrect equation for maximized log likelihood was duplicated from the entropy equation.
Main Results:
- The equation for maximized log likelihood was found to be incorrect.
- The error has been rectified in the updated versions of the article.
Conclusions:
- The correction ensures the integrity of the INSIGHT tool's statistical analysis.
- Accurate entropy measurement is vital for downstream biological interpretations.
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