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Desensitization therapy using 'Mariana Castells' protocol in a patient with multiple autoimmune disorders- does it
Syed Raza Shah1, Terance Millan1, Sardar Muhammad Alamzaib1
1Department of Internal Medicine, North Florida Regional Medical Center, University of Central Florida (Gainesville), Gainesville, USA.
Journal of Community Hospital Internal Medicine Perspectives
|February 22, 2019
Summary
Antibiotic hypersensitivity reactions can be managed with specialized desensitization protocols, even in patients with mast cell activation syndrome and autoimmune diseases. This approach ensures safe and effective treatment for critical infections.
Area of Science:
- Clinical Medicine
- Pharmacology
- Immunology
Background:
- Widespread antibiotic use increases hypersensitivity reactions, complicating treatment for infectious diseases.
- Hypersensitivity reactions range from mild skin issues to life-threatening anaphylaxis, often necessitating alternative therapies.
- Patients with mast cell activation syndrome and autoimmune diseases present unique challenges for antibiotic therapy due to potential hypersensitivity.