A 10-year Retrospective Descriptive Study on Pure Neuritic Leprosy from a Tertiary Referral Centre

Pure neuritic leprosy is a risk factor for grade 2 disability owing to the early nerve damage.

To study the clinical patterns of neuritic leprosy, to determine the percentage of patients manifesting grade 2 disability at the time of diagnosis and to identify any risk factors for the same.

Retrospective descriptive study from previous case records of pure neuritic leprosy patients who attended a tertiary centre from 1^st July 2007 to 30^th June 2017.

Data on patients who satisfied the World Health Organization (WHO) cardinal criteria for diagnosis of leprosy, who had no skin lesion of leprosy and had acid-fast bacilli negative status on skin smears were collected using a pre-set proforma.

The Chi-square test was used to assess statistical significance and logistic regression model was applied to avoid the effects of confounding factors.

A diagnostic delay of >1 year was observed in 44% patients. At the time of diagnosis, grade 2 disability was documented in 60 (80%) of patients. No statistically significant risk factor was identified for grade 2 disability.

Retrospective nature and the study conducted in a tertiary care centre not reflecting the status in the community were the limitations.

Grade 2 disability noted in 80% of patients points to the inherent nature of disease to cause early nerve damage. Diagnostic delay of >1 year documented in 44% of patients underscores the diagnostic challenges in the absence of skin lesions.