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Related Experiment Video

Updated: Jan 28, 2026

Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes
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Chorioretinal folds: a proposed diagnostic algorithm.

Alessandro Bagnis1,2, Carlo Alberto Cutolo3,4, Guido Corallo3

  • 1Clinica Oculistica, DiNOGMI, Università degli Studi di Genova, Viale Benedetto XV 5, 16132, Genoa, Italy. alebagnis@libero.it.

International Ophthalmology
|February 22, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a diagnostic algorithm to effectively manage chorioretinal folds. The algorithm helps optimize investigations for identifying underlying causes of these fundus abnormalities.

Keywords:
Chorioretinal foldsOcular diseasesSystemic diseases

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Area of Science:

  • Ophthalmology
  • Medical Diagnostics

Background:

  • Chorioretinal folds are fundus striations, often horizontal and parallel.
  • They can be unilateral or bilateral, symptomatic or asymptomatic.
  • Associated pathologies include ocular, extra-ocular, and systemic diseases (e.g., autoimmune disorders, intracranial hypertension).

Purpose of the Study:

  • To develop a diagnostic algorithm for managing chorioretinal folds.
  • To optimize the selection and number of diagnostic investigations.

Main Methods:

  • Literature review focusing on chorioretinal folds and associated conditions.
  • Development of a diagnostic algorithm based on reviewed data.

Main Results:

  • Chorioretinal folds present as visible fundus striations.
  • While 'idiopathic' folds exist, improved diagnostics reveal underlying causes more frequently.
  • The algorithm aims to streamline the diagnostic process.

Conclusions:

  • Chorioretinal folds can indicate serious underlying conditions requiring multidisciplinary care.
  • An appropriate work-up tailored to clinical features is essential.
  • A diagnostic algorithm aids in optimizing the approach to etiology and treatment.