Related Experiment Videos
Mylicon drops in the treatment of infant colic
N Becker1, P Lombardi, E Sidoti
1Albert Einstein College of Medicine, New York, New York.
Insights
Simethicone, marketed as Mylicon Drops, effectively treats infant colic. Most infants experienced symptom improvement or resolution within seven days, enhancing infant and family quality of life.
Area of Science:
- Pediatrics
- Pharmacology
Background:
- Infant colic is a common condition affecting newborns.
- Effective treatments for infant colic are sought after by caregivers.
- Simethicone is a widely used over-the-counter medication for gas relief.
Purpose of the Study:
- To evaluate the efficacy of simethicone (Mylicon Drops) in treating infant colic.
- To assess the impact of simethicone on infant colic symptoms and overall quality of life.
Main Methods:
- An open-label trial involving 51 healthy infants aged 2-12 weeks.
- A one-week study period with caregiver-reported outcomes.
- Dosage administered: 0.3 ml of simethicone with each feeding.
Main Results:
- Symptom improvement or resolution observed in 78% of infants after one day.
- Symptom improvement or resolution observed in 86% of infants after seven days.
- Caregivers reported noticeable improvements in infant and family quality of life.
Conclusions:
- Simethicone (Mylicon Drops) is highly effective in managing infant colic symptoms.
- Treatment with simethicone significantly improves the quality of life for both infants and their families.
- The recommended dosage of 0.3 ml with each feeding is associated with positive outcomes.
Abstract:
The efficacy of simethicone (available in liquid form as Mylicon Drops) in the treatment of infant colic was assessed in 51 healthy infants between 2 and 12 weeks of age. The open-label trial consisted of a one-week study period. Care-givers were to report on the infant's response to treatment after one day and one week of treatment, and in terms of the overall quality of life of both infant and family. Symptoms of colic improved or resolved in 38 infants (78%) after one day of treatment and in 44 (86%) after seven days. On both days, caregivers also noted that the quality of family life was noticeably improved. Mylicon Drops, in a dose of 0.3 ml with each feeding, can cause improvement or complete resolution of the symptoms of infant colic in the vast majority of patients and a better quality of life for both infant and family.