Related Experiment Video
Updated: Jan 28, 2026
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
A review on coronary artery disease, its risk factors, and therapeutics
Arup Kr Malakar1, Debashree Choudhury1, Binata Halder1
1Department of Biotechnology, Assam University, Silchar, Assam, India.
Insights
Coronary artery disease (CAD) is a leading cause of death globally, influenced by lifestyle, environment, and genetics. Understanding risk factors and genetic links like chromosome 9p21.3 aids in managing and preventing this major cardiovascular disease.
Area of Science:
- Cardiology
- Genetics
- Public Health
Background:
- Coronary artery disease (CAD) is a primary cause of mortality worldwide.
- Risk factors include lifestyle, environmental, and genetic predispositions.
- Identifying risk factors in healthy populations predicts future CAD occurrence.
Purpose of the Study:
- To highlight the significance of CAD as a global health issue.
- To discuss the known risk factors contributing to CAD.
- To mention the genetic associations, specifically chromosome 9p21.3, in premature CAD.
Main Methods:
- Review of existing literature on CAD prevalence and risk factors.
- Analysis of genome-wide association studies (GWAS) for genetic links.
- Examination of therapeutic strategies for symptomatic relief.
Main Results:
- CAD is a major cause of death in developed and developing nations.
- Chromosome 9p21.3 is associated with premature CAD onset.
- Established risk factors include diabetes, hypertension, smoking, hyperlipidemia, obesity, homocystinuria, and stress.
Conclusions:
- CAD management and eradication are supported by extensive research.
- Various therapeutic agents are available for symptomatic angina relief.
- Continued research into risk factors and genetics is crucial for CAD prevention.
Abstract:
Coronary artery disease (CAD) is one of the major cardiovascular diseases affecting the global human population. This disease has been proved to be the major cause of death in both the developed and developing countries. Lifestyle, environmental factors, and genetic factors pose as risk factors for the development of cardiovascular disease. The prevalence of risk factors among healthy individuals elucidates the probable occurrence of CAD in near future. Genome-wide association studies have suggested the association of chromosome 9p21.3 in the premature onset of CAD. The risk factors of CAD include diabetes mellitus, hypertension, smoking, hyperlipidemia, obesity, homocystinuria, and psychosocial stress. The eradication and management of CAD has been established through extensive studies and trials. Antiplatelet agents, nitrates, β-blockers, calcium antagonists, and ranolazine are some of the few therapeutic agents used for the relief of symptomatic angina associated with CAD.
More Related Videos
04:40Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
Published on: April 24, 2017
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
01:26Coronary Artery Disease II: Pathophysiology
01:27Coronary Artery Disease V: Interprofessional Care
01:30Coronary Artery Disease III: Clinical Manifestations
01:26Coronary Artery Disease IV: Preventive Measures
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...