Related Experiment Video
Updated: Jan 28, 2026

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
Published on: November 27, 2016
Enhancement of bile resistance by maltodextrin supplementation in Lactobacillus plantarum Lp-115
1Department of Food Science and Technology, School of Bioengineering, East China University of Science and Technology, Shanghai, China.
Aims:
To identify the mechanism in which way maltodextrin enhance bile tolerance in Lactobacillus plantarum Lp-115.
Methods And Results:
Based on determining the OD600 value and counting the numbers of viable cells by the pour plate method, the results showed that maltodextrin could not promote the strain growth directly, but could enhance the tolerance of bile in Lp-115. The OD600 value of L. plantarum Lp-115 cultured in MRSB broth with maltodextrin was three times higher than the control value. After supplementing the medium with 4·0% maltodextrin, the highest survival rate was observed when the bile concentration is 0.3%.
Conclusions:
In summary, maltodextrin exhibited a significant improvement of bile tolerance and it could enhance cell hydrophobicity, shift the fatty acid composition of the membrane and induce the expression of a bile salt hydrolase gene (pva3) significantly.
Significance And Impact Of The Study:
This is the first report concerning the mechanism of maltodextrin enhancing the bile tolerance. This study promotes the application of maltodextrin as a choice to protect probiotic L. plantarum strains against the bile salt stress.
Related Concept Videos
Bile
Bile is released when dietary fats enter...
Resistivity
Resistance
Self-Evaluation: Self-Enhancement and Self-Verification
Equivalent Resistance
Resistance and Conductance
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...

