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Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor

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Automated Chemical Sensing Unit Integration for Parallel Optical Interrogation.

Ana L Hernandez¹, Fabian Dortu², Theo Veenstra³

¹Centre for Biomedical Technology, Optics, Photonics and Biophotonics Laboratory, Campus Montegancedo, Universidad Politécnica de Madrid, 28223 Madrid, Spain. Ana.lopez@upm.es.

Sensors (Basel, Switzerland)

|February 23, 2019

Summary

This study presents an automated optical sensing unit for simultaneous, in-situ detection of oceanic chemical pollutants using resonant nanopillars. The system achieved high sensitivity and real-time multiplexed measurements, demonstrating its potential for environmental monitoring.

Keywords:

automatic system microfluidics optical sensor parallel detection resonant nanopillars sensing

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Published on: March 10, 2020

Area of Science:

Environmental Science
Nanotechnology
Optical Sensing

Background:

Oceanic pollution monitoring requires sensitive, in-situ detection methods.
Existing technologies may lack the multiplexing capability for simultaneous analysis of diverse chemical pollutants.

Purpose of the Study:

To develop and demonstrate an automated optical sensing unit for parallel, in-situ detection of multiple chemical pollutants in oceanic waters.
To validate the performance of a novel sensing chip based on resonant nanopillars (R-NPs).

Main Methods:

Integration of an automated chemical optical sensing unit with a 12-channel spectrometer and an embedded computer-on-chip.
Design of a sensing chip with twelve biophotonic sensing cells (BICELLs) utilizing R-NP transducers.
Implementation of a microfluidic system with automated flow control for complex experimental protocols.

Main Results:

The system successfully performed parallel interrogation of 12 BICELLs, acquiring and analyzing 12 spectra simultaneously.
Demonstrated bulk sensitivity of 285.9 ± 16.4 nm/RIU and a Limit of Detection (LoD) of 2.95 × 10^-6 RIUs.
Achieved real-time sensogram acquisition under continuous flow, showcasing the unit's multiplexed detection capability.

Conclusions:

The developed automated optical sensing unit shows high potential for in-situ, multiplexed, and automatic optical biosensing of chemical pollutants.
The R-NP based sensing chip offers a robust platform for simultaneous environmental monitoring.
This technology advances the capability for real-time assessment of oceanic water quality.