Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rational Expressions01:28

Rational Expressions

382
Rational expressions are algebraic fractions in which both the numerator and the denominator are polynomials. These expressions follow the arithmetic rules of numerical fractions but require extra care due to the presence of variables. A fundamental part of working with rational expressions is identifying values that make the expression undefined, typically those that result in division by zero or undefined radicals.Determining the DomainThe domain of a rational expression includes all real...
382
Rationalizing Substitutions01:29

Rationalizing Substitutions

57
Integrals involving non-rational functions are often difficult to evaluate using standard techniques, especially when radicals appear in the integrand. Rationalizing substitution provides a systematic method for simplifying such integrals by converting them into rational forms that are easier to handle.Consider a rod whose linear mass density depends on a constant linear density, a characteristic length, and the distance from the left end of the rod. Determining the total mass requires...
57
Asymptotes in Rational Functions01:30

Asymptotes in Rational Functions

250
A rational function is defined as the quotient of two polynomials:  where Q(x)≠0, These functions often exhibit asymptotes, which are the lines that the graph approaches but never touches. These asymptotes are classified based on how the function behaves near specific values of the input.Vertical asymptotes occur where the denominator is zero, and the numerator is not, causing the function to be undefined. These are found by solving Q(x)=0. For example:  has a vertical...
250
Rational Emotive Behavior Therapy01:24

Rational Emotive Behavior Therapy

417
Cognitive-behavioral therapies (CBTs) are grounded in the belief that our thoughts profoundly influence our emotions and actions. Advocates of CBT emphasize three core assumptions: first, that cognitions are identifiable and measurable; second, that they are central to psychological functioning; and third, that irrational or maladaptive beliefs can be replaced with rational and adaptive ones. This transformative approach to therapy has paved the way for specific models such as Albert...
417
Integration of Rational Functions Using Partial Fractions01:29

Integration of Rational Functions Using Partial Fractions

72
Rational functions are expressions written as the ratio of two polynomials, and their integrals are evaluated by simplifying the integrand into manageable parts. These functions are classified as proper or improper based on the degrees of the numerator and denominator.A rational function is proper when the degree of the numerator is less than the degree of the denominator. In this case, partial fraction decomposition is used to rewrite the function as a sum of simpler rational terms. The...
72
Rational Dosage Regimen: Maintenance Dose and Loading Dose01:24

Rational Dosage Regimen: Maintenance Dose and Loading Dose

5.4K
A rational dosage regimen considers a drug's pharmacokinetics, including its absorption, distribution, metabolism, and elimination from the body. By understanding these factors, the appropriate dosage can be determined, and the dosing schedule can be designed to achieve and maintain the desired therapeutic effect while minimizing adverse effects.
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
5.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of economic sanctions on child health in Cuba.

BMJ paediatrics open·2026
Same author

Impact of hospital payment reform on rational use of antibiotics: a natural experiment.

Frontiers in public health·2025
Same author

Profiting from death: the arms trade.

BMJ paediatrics open·2025
Same author

Advertising and child health.

BMJ paediatrics open·2025
Same author

Patient-reported outcome measures for medication treatment satisfaction: a systematic review of measure development and measurement properties.

BMC medicine·2024
Same author

Global, regional and national availability of essential medicines for children, 2009-2020: a systematic review and meta-analysis.

BMC public health·2023

Related Experiment Video

Updated: Jan 28, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.4K

Modifying a Paediatric Rational Prescribing Tool (POPI) for Use in the UK.

Fenella Corrick1, Imti Choonara2, Sharon Conroy3

  • 1Division of Medical Sciences & Graduate Entry Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby, DE22 3DT, UK. fenella.corrick@nottingham.ac.uk.

Healthcare (Basel, Switzerland)
|February 23, 2019
PubMed
Summary

A new tool, the modified POPI (UK), evaluates rational prescribing in UK pediatric care. It adapts a French tool with 80 criteria, making it the first of its kind for evaluating pediatric prescribing quality in UK hospitals and clinics.

Keywords:
childrenpaediatricrational prescribinguse of medicines

More Related Videos

Traditional Trail Making Test Modified into Brand-new Assessment Tools: Digital and Walking Trail Making Test
08:07

Traditional Trail Making Test Modified into Brand-new Assessment Tools: Digital and Walking Trail Making Test

Published on: November 23, 2019

11.8K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

7.2K

Related Experiment Videos

Last Updated: Jan 28, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.4K
Traditional Trail Making Test Modified into Brand-new Assessment Tools: Digital and Walking Trail Making Test
08:07

Traditional Trail Making Test Modified into Brand-new Assessment Tools: Digital and Walking Trail Making Test

Published on: November 23, 2019

11.8K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

7.2K

Area of Science:

  • Pharmacology
  • Pediatric Medicine
  • Health Services Research

Background:

  • Rational prescribing tools are crucial for evaluating and improving medication use in healthcare.
  • Existing tools for assessing pediatric rational prescribing are limited, with only one identified previously.
  • The Pediatrics: Omission of Prescriptions and Inappropriate Prescriptions (POPI) tool exists but requires adaptation for international use.

Purpose of the Study:

  • To adapt the French POPI tool for evaluating rational prescribing in United Kingdom (UK) pediatric practice.
  • To ensure the modified tool aligns with current UK clinical guidelines and terminology.
  • To establish the first dedicated rational prescribing evaluation tool for UK pediatric settings.

Main Methods:

  • A literature search identified the existing POPI tool and relevant UK clinical guidelines (NICE, SIGN, BNFC).
  • POPI criteria were systematically compared against UK guidelines.
  • Criteria were modified, consolidated, or omitted based on concordance with UK guidance, resulting in a reduced criterion set.

Main Results:

  • The modified POPI (UK) tool contains 80 criteria, a reduction from the original 105.
  • 49 criteria remained unchanged, 29 were modified to align with UK guidelines.
  • 23 criteria were omitted due to lack of UK guidance or conflicting practice, including the 'mosquitos' category.

Conclusions:

  • The modified POPI (UK) tool is the first rational prescribing evaluation tool specifically designed for UK pediatric settings.
  • This tool facilitates the assessment of prescribing quality in both hospital and outpatient pediatric care in the UK.
  • The adaptation process ensures clinical relevance and adherence to UK-specific healthcare standards.