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Molecular genetic approaches to the pathogenesis of bacillary dysentery
M Yoshikawa1, C Sasakawa, S Makino
1Institute of Medical Science, University of Tokyo, Japan.
Abstract:
Bacillary dysentery is an invasive infectious disease of the human colon. At least three genetic loci on the chromosome and a huge plasmid have been implicated in its pathogenesis. Results obtained from molecular genetic studies, mainly of the genes, virG, virF and kcpA are discussed.