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Need for Obtaining Pure Cultures

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Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Published on: November 17, 2011

Sculpting stable structures in pure liquids.

Tadej Emeršič¹, Rui Zhang², Žiga Kos³

¹Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.

Science Advances

|February 23, 2019

Summary

This summary is machine-generated.

Researchers engineered liquid crystals into stable, reconfigurable domains using microfluidics and light. These sculpted liquids offer potential for advanced microfluidic devices and selective particle encapsulation.

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Area of Science:

Soft Matter Physics
Materials Science
Microfluidics

Background:

Pure liquids are structurally homogeneous under thermodynamic equilibrium.
Liquid crystals can form ordered domains using flow and light pulses.
Controlling domain formation in liquids is crucial for advanced applications.

Purpose of the Study:

To demonstrate precise control over the nucleation, growth, and shape of polar ordered domains in liquid crystals.
To investigate the stabilization of these engineered liquid structures.
To explore potential applications in microfluidic devices.

Main Methods:

Utilized concerted microfluidic flows for precise liquid manipulation.
Employed localized optothermal fields to control domain formation.
Combined experimental, theoretical, and simulation approaches.
Maintained liquids in a controlled nonequilibrium state for stabilization.

Main Results:

Achieved complete control over domain nucleation, growth, and shape.
Demonstrated indefinite stabilization of engineered liquid structures.
Created reconfigurable domains with polar order within liquid crystals.

Conclusions:

Engineered liquid crystals can form stable, reconfigurable domains with polar order.
Controlled nonequilibrium states are key to stabilizing these sculpted liquids.
Potential applications include microfluidic devices for selective encapsulation and stimuli-responsive compartments.