Related Experiment Video

Updated: Jan 28, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

622

Neurodevelopmental Outcomes of Very Low Birth Weight Infants at 18-24 Months, Corrected Gestational Age in a Tertiary

Samuel P Oommen1, Sridhar Santhanam2, Hima John2

  • 1Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India.

Journal of Tropical Pediatrics
|February 23, 2019
PubMed

Insights

Poor post-natal growth impacts neurodevelopment in very low birth weight (VLBW) infants. This study found 10.31% of VLBW survivors had poor outcomes, with growth being a key factor.

Area of Science:

  • Neonatology
  • Developmental Pediatrics
  • Public Health

Background:

  • Very low birth weight (VLBW) infants face significant risks for adverse neurodevelopmental outcomes.
  • Understanding regional variations in outcomes and risk factors is crucial for targeted interventions.

Purpose of the Study:

  • To determine the prevalence of poor neurodevelopmental outcomes in VLBW survivors in South India.
  • To identify risk factors associated with these outcomes.

Main Methods:

  • A cohort of 643 VLBW survivors was identified.
  • Neurodevelopmental outcomes were assessed in 422 infants up to 24 months of age.
  • Multivariate analysis was used to identify independent risk factors.

Main Results:

  • 10.31% of assessed VLBW infants (359 children) exhibited poor neurodevelopmental outcomes.
  • Poor post-natal growth was significantly associated with poor neurodevelopmental outcomes (p=0.045).
  • Cerebral palsy, visual, and hearing impairments were noted in 1.67%, 0.28%, and 0.28% of infants, respectively.

Conclusions:

  • A substantial proportion of VLBW infants in this South Indian cohort experienced poor neurodevelopmental outcomes.
  • Poor post-natal growth emerged as a critical determinant of developmental outcomes, independent of neonatal complications.
  • These findings highlight the need for focused growth monitoring and support for VLBW infants.
Abstract

More Related Videos

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

755
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.1K

Related Concept Videos

Tertiary Healthcare System01:21

Tertiary Healthcare System

Specialized care provided over an extended period is called tertiary care. Usually, a primary or secondary care physician will refer a patient to tertiary care. A patient's maximum physical and mental function is restored in tertiary care, which is caused due to the impact of a chronic illness or condition. Tertiary care aims to achieve the highest level of functioning possible while managing chronic illness. For example, a patient who falls and fractures their hip will need secondary care...
2.2K
Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
6.7K
Distance Corrections01:15

Distance Corrections

To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
282
Nomenclature of Secondary and Tertiary Amines01:12

Nomenclature of Secondary and Tertiary Amines

The secondary and tertiary amines are derivatives of ammonia, where two and three of its hydrogens are replaced by alkyl groups, respectively. Secondary and tertiary amines can be symmetrical with identical alkyl groups attached to the nitrogen atom or unsymmetrical when more than one type of alkyl group is present. The standard nomenclature of secondary and tertiary amines is similar to the names given to the primary amines. They are generally named alkylamines. As depicted in Figure 1, for...
5.1K
Power Factor Correction01:20

Power Factor Correction

The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
532
Weighted Mean00:57

Weighted Mean

While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
6.3K