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Linear porokeratosis associated with Bardet-Biedl syndrome: A case report
Anna C Tappel1, Nitin Tiwari2, Barrett Zlotoff2
1University of Virginia School of Medicine, Charlottesville, Virginia.
Abstract:
This case report presents a 17-year-old boy with Bardet-Biedl syndrome (BBS) and a long-standing hyperpigmented eruption on the left trunk and upper extremity, clinically and histologically consistent with linear porokeratosis (LP). BBS patients frequently require solid organ transplant, and subsequent immunosuppression places them at especially high risk for malignant transformation of premalignant skin lesions such as LP. Although BBS affects multiple organ systems, there are only a handful of case reports detailing associated cutaneous involvement, and, to our knowledge, this is the first reported case of linear porokeratosis occurring in patient with BBS.
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