Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Breast cancer.

C L Loprinzi, P P Carbone

    Cancer Chemotherapy and Biological Response Modifiers
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Oral contraceptives do not raise breast cancer risk. Most women with premalignant breast lesions fare well long-term, and various treatments offer comparable outcomes, though consensus on adjuvant therapy remains elusive.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Chemotherapy-induced peripheral neuropathy: ice, compression, both, or neither?

    Annals of oncology : official journal of the European Society for Medical Oncology·2020
    Same author

    The past and future of 'reported outcomes' in studies on chemotherapy neuropathy.

    Annals of oncology : official journal of the European Society for Medical Oncology·2017
    Same author

    Cancer-Associated Anorexia and Cachexia : Implications for Drug Therapy.

    Drugs·2017
    Same author

    Statistical controversies in clinical research: Value of adverse events relatedness to study treatment: analyses of data from randomized double-blind placebo-controlled clinical trials.

    Annals of oncology : official journal of the European Society for Medical Oncology·2017
    Same author

    Endpoint comparison for bone mineral density measurements in North Central Cancer Treatment Group cancer clinical trials N02C1 and N03CC (Alliance).

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Survival following early-stage colon cancer: an ACCENT-based comparison of patients versus a matched international general population†.

    Annals of oncology : official journal of the European Society for Medical Oncology·2015
    Same journal

    Native and genetically engineered anti-disialoganglioside monoclonal antibody treatment of melanoma.

    Cancer chemotherapy and biological response modifiers·2005
    Same journal

    Human tumor associated antigen mimicry by xenoantigens, anti-idiotypic antibodies and peptide mimics: implications for immunotherapy of malignant diseases.

    Cancer chemotherapy and biological response modifiers·2005
    Same journal

    DNA vaccines for melanoma.

    Cancer chemotherapy and biological response modifiers·2005
    Same journal

    Immunizing against partially defined antigen mixtures, gangliosides, or peptides to induce antibody, T cell, and clinical responses.

    Cancer chemotherapy and biological response modifiers·2005
    Same journal

    Chemotherapy, cytokines, and biochemotherapy for melanoma.

    Cancer chemotherapy and biological response modifiers·2005
    Same journal

    Current status of interferon-alpha in the treatment of melanoma.

    Cancer chemotherapy and biological response modifiers·2005
    See all related articles

    Area of Science:

    • Oncology
    • Breast Cancer Research
    • Clinical Trials

    Background:

    • Breast cancer management involves diverse therapeutic strategies and ongoing research into risk factors and prognostics.
    • Understanding treatment efficacy and patient outcomes is crucial for advancing breast cancer care.

    Purpose of the Study:

    • To synthesize current findings on breast cancer, covering risk factors, treatment modalities, and prognostic indicators.
    • To highlight areas of consensus and divergence in recent breast cancer research and clinical recommendations.

    Main Methods:

    • Review of recent manuscripts and consensus conference conclusions pertaining to breast cancer.
    • Analysis of data on oral contraceptive use, premalignant lesions, surgical techniques, and adjuvant therapies.

    Related Experiment Videos

    Main Results:

    • Oral contraceptives show no increased risk for breast cancer.
    • Premalignant lesions generally have favorable long-term outcomes post-resection.
    • Both breast-conserving surgery with radiation and mastectomy with reconstruction yield satisfactory cosmetic results.
    • Thymidine labeling index aids in prognosis; immunohistochemistry accurately measures estrogen receptors.
    • Hormonal therapies demonstrate similar efficacy; idarubicin and lonidamine warrant further investigation.
    • No single combination chemotherapy regimen is definitively superior; consensus on adjuvant therapy is lacking.
    • Inflammatory breast cancer patients show improved survival with initial combination chemotherapy.
    • Locally recurrent breast cancer patients have better prognoses after lumpectomy/irradiation versus mastectomy.

    Conclusions:

    • Current research provides insights into breast cancer risk, treatment options, and prognostic factors.
    • Discrepancies exist in consensus recommendations for adjuvant breast cancer therapy.
    • Advances in chemotherapy and surgical approaches offer improved outcomes for specific breast cancer subtypes.