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Related Concept Videos

Drug Delivery: Overview01:16

Drug Delivery: Overview

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug Delivery: Enteral Route01:18

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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
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Drug Delivery: Miscellaneous Routes01:22

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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Frustration and Conflict: Approach-Approach, Approach-Avoidance01:20

Frustration and Conflict: Approach-Approach, Approach-Avoidance

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Frustration occurs when people are obstructed or prevented from achieving a desired goal or fulfilling a perceived need. For example, when someone's input is ignored in a discussion, it can lead to feelings of frustration. Conflict, however, arises from opposing interests, goals, or actions. Conflicts can take various forms based on the nature of these opposing desires or goals.
One common type of conflict is the Approach–Approach Conflict. In this case, a person faces two desirable...
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Actuarial Approach01:20

Actuarial Approach

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The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
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Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice
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E-drug delivery: a futuristic approach.

Khushwant S Yadav1, Sonali Kapse-Mistry2, G J Peters3

  • 1Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS Deemed to be University, Vile-Parle (W), Mumbai 400056, India.

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Electronic drug delivery systems improve patient compliance and treatment, especially for chronic diseases. Innovations like wearable devices and smartphone apps are personalizing healthcare through advanced drug administration technologies.

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Area of Science:

  • Biomedical Engineering
  • Pharmaceutical Sciences
  • Digital Health

Background:

  • Traditional drug delivery methods face challenges in patient compliance and precise dosage control.
  • Chronic and age-related diseases require continuous and accurate medication management.
  • Technological advancements are driving innovation in drug delivery systems.

Purpose of the Study:

  • To review the evolving landscape of electronic drug delivery (E-drug delivery) systems.
  • To highlight how technology enhances patient comfort and treatment efficacy.
  • To explore the potential of personalized drug delivery in future healthcare.

Main Methods:

  • Literature review of recent advancements in E-drug delivery.
  • Analysis of applications in various medical fields, including anesthesia, GI tracking, epilepsy, insulin delivery, cardiac ailments, and cancer therapy.
  • Examination of emerging technologies like wearable systems and smartphone integration.

Main Results:

  • E-drug delivery systems offer precise dose regulation and improved monitoring capabilities.
  • Applications span diverse therapeutic areas, demonstrating broad utility.
  • Wearable technology and mobile apps are enhancing patient engagement and remote management.
  • Personalized drug delivery is emerging as a key trend.

Conclusions:

  • Technological integration in drug delivery significantly improves patient comfort and compliance.
  • E-drug delivery systems are pivotal for managing chronic conditions and advancing personalized medicine.
  • The future of healthcare will be shaped by intelligent, personalized drug administration solutions.