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[Risk Factors for Permanent Postoperative Hypoparathyreoidism]
Erik H Allemeyer1, Marielle S Kossow1, Burkhard Riemann2
1Klinik für Allgemein- u. Viszeralchirurgie mit Sektion Proktologie, Raphaelsklinik Münster, Deutschland.
Zentralblatt Fur Chirurgie
|February 23, 2019
Summary
Permanent hypoparathyroidism after thyroidectomy is common. Low PTH on day 1, no drain, and longer hospital stays are risk factors for this complication.
Area of Science:
- Endocrinology
- Surgical Outcomes
- Thyroid Surgery
Background:
- Permanent hypoparathyroidism is a frequent complication of total thyreoidectomy.
- It leads to significant long-term morbidity, reduced quality of life, and economic burden.
Purpose of the Study:
- To identify risk factors associated with permanent postoperative hypoparathyroidism following total thyreoidectomy.
Main Methods:
- Retrospective study of 382 patients who underwent total thyreoidectomy.
- Follow-up investigation for 117 patients between 8 and 32 months postoperatively.
Main Results:
- Low parathyroid hormone (PTH) levels on postoperative day 1 were associated with permanent hypoparathyroidism.
- Non-application of a drain and prolonged postoperative hospital stay were also identified as associated factors.
- No significant association was found between autotransplantation of parathyroid glands and the complication.
Conclusions:
- Key associated factors for permanent postoperative hypoparathyroidism were identified.
- Larger multicenter studies are recommended for validation of these risk factors.
- Understanding these factors can aid in preventing the complication and guiding patient management.
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