Related Experiment Video
Updated: Jan 28, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Prototype of running clinical trials in an untrustworthy environment using blockchain
Daniel R Wong1,2, Sanchita Bhattacharya1,2, Atul J Butte3,4,5
1Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, 94158, USA.
Abstract:
Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system. We propose a blockchain-based system to make data collected in the clinical trial process immutable, traceable, and potentially more trustworthy. We use raw data from a real completed clinical trial, simulate the trial onto a proof of concept web portal service, and test its resilience to data tampering. We also assess its prospects to provide a traceable and useful audit trail of trial data for regulators, and a flexible service for all members within the clinical trials network. We also improve the way adverse events are currently reported. In conclusion, we advocate that this service could offer an improvement in clinical trial data management, and could bolster trust in the clinical research process and the ease at which regulators can oversee trials.
More Related Videos
13:59Reduced-gravity Environment Hardware Demonstrations of a Prototype Miniaturized Flow Cytometer and Companion Microfluidic Mixing Technology
Published on: November 13, 2014
05:16Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
Published on: May 7, 2020
Related Concept Videos
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Statistical Software for Data Analysis and Clinical Trials
Concepts and Prototypes
The brain organizes this information using concepts, which are mental categories grouping linguistic data,...
Wald-Wolfowitz Runs Test II
For binary data, runs are identified using symbols such as + and −, or equivalently, 1s and 0s. In...
Wald-Wolfowitz Runs Test I
The test works...