Related Experiment Video
Updated: Jan 28, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
[Treatment options for progressive myopia in childhood]
1Klinik für Augenheilkunde, Medizinische Fakultät, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.
Worldwide myopia incidence is rising, threatening vision and straining healthcare. Early optical and pharmacological treatments in children and adolescents can reduce myopia progression by up to 50% with a good side effect profile.
Area of Science:
- Ophthalmology
- Optometry
- Public Health
Background:
- The global incidence of myopia (nearsightedness) is increasing.
- This rise presents significant challenges due to associated secondary and vision-threatening eye diseases.
- Myopia onset typically occurs in childhood and adolescence, making this period critical for intervention.
Purpose of the Study:
- To provide an overview of current optical and pharmacological treatment options for myopia.
- To highlight interventions that can influence myopia progression during developmental years.
- To assess the efficacy and side effect profiles of these treatments.
Main Methods:
- Review of existing literature on myopia management strategies.
- Analysis of optical interventions (e.g., special contact lenses, spectacle lenses).
- Evaluation of pharmacological treatments (e.g., low-dose atropine).
Main Results:
- Identified optical and pharmacological treatments can reduce myopia progression.
- Average effect sizes indicate up to 50% reduction in progression.
- Treatments demonstrate a comparatively favorable side effect profile.
Conclusions:
- Early intervention during childhood and adolescence is crucial for managing myopia progression.
- Optical and pharmacological treatments offer effective strategies with manageable side effects.
- These interventions can mitigate the long-term risks associated with high myopia.
Related Concept Videos
Erikson's Theory on Socioemotional Development during Childhood
The first four of Erikson's eight...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Piaget's Theory of Cognitive Development from Childhood into Adulthood
Schemata: Building Blocks of Knowledge
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Treatment Resistant Cancers

