Related Experiment Video

Updated: Jan 28, 2026

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
04:40

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Published on: January 5, 2024

3.2K

Diagnosis of cerebral venous thrombosis: a single centre experience

Petr Mikulenka1, Tomas Peisker1, Peter Vasko1

  • 1Department of Neurology, Third Faculty of Medicine, Charles University and Faculty Hospital Kralovske Vinohrady, Prague, Czech Republic.

Neuro Endocrinology Letters
|February 24, 2019
PubMed

Insights

Delayed diagnosis of cerebral venous thrombosis (CVT) is common due to varied symptoms. Identifying risk factors and atypical headaches prompts timely diagnosis via imaging, improving patient outcomes.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Diagnostic Imaging

Background:

  • Cerebral venous thrombosis (CVT) is a critical cerebrovascular condition often presenting with non-specific symptoms, leading to diagnostic delays.
  • The variability in clinical presentation and rarity of CVT contribute to challenges in early identification.

Purpose of the Study:

  • To elucidate the risk factors associated with cerebral venous thrombosis.
  • To characterize the initial clinical manifestations and diagnostic findings of CVT.
  • To evaluate the role of imaging modalities in confirming CVT diagnoses.

Main Methods:

  • Retrospective analysis of 34 patients diagnosed with CVT between 2004 and 2016.
  • Review of demographic data, clinical symptoms, D-dimer levels, risk factors, and Magnetic Resonance (MR) findings.
  • Assessment of time from symptom onset to diagnosis.

Main Results:

  • Headache was the most frequent initial symptom (82.4%).
  • Focal neurological deficits or encephalopathy occurred in 64.7% of patients.
  • Risk factors were identified in 76.5% of patients, including hormonal contraceptive use (68% in women of childbearing potential) and recent inflammation.
  • MR venography confirmed CVT in all cases.
  • Hereditary thrombophilia was present in 68% of tested patients.
  • Elevated D-dimer levels were observed in 86% of cases.
  • The average diagnostic delay was 6.9 days.

Conclusions:

  • Cerebral venous thrombosis exhibits a diverse clinical course, frequently resulting in delayed diagnosis.
  • Atypical headaches and the presence of risk factors are crucial indicators for initiating diagnostic imaging for CVT.
  • Prompt recognition and appropriate imaging are essential for timely CVT diagnosis and management.
Abstract

More Related Videos

Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis06:03

Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis

Published on: July 12, 2011

17.7K
Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

16.1K

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
433
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
307
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
242
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
335
Venous Return01:04

Venous Return

The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.2K
Nursing Diagnosis01:22

Nursing Diagnosis

Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...
4.0K