Related Experiment Video
Updated: Jan 28, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Dehydration: A Multidisciplinary Case-Based Discussion for First-Year Medical Students
Yerko Berrocal1, Jonathan Fisher2, Jenna Regan2
1Associate Professor, Health Sciences Education Department, University of Illinois College of Medicine.
Introduction:
As many medical school curricula shift to integrated learning of multiple basic science topics as well as clinical concepts, there is an increasing need for instructional materials that incorporate multiple topics yet are targeted to the knowledge basis of first-year medical students. This interactive case-based session for first-year medical students centers on the clinical presentation and initial evaluation of a patient experiencing dehydration after running a marathon in a high-altitude city.
Methods:
After completion of assigned out-of-class preparation, students followed the patient from a healthy state to moderate dehydration over the course of two 2-hour class sessions. Throughout discussion of the case, students answered questions requiring them to integrate elements of cell biology, biochemistry, physiology, and clinical reasoning with minimal faculty involvement. The learning activity was administered at University of Illinois College of Medicine campuses in both a small-group setting (10 students, one faculty facilitator) and a large-group format (55-90 students, multiple faculty facilitators). Following the activity, we assessed student perceptions of the design and implementation of the materials as well as effectiveness at meeting the learning goals.
Results:
Of 198 students who participated in the case discussions on dehydration, the majority rated the case positively, indicated by a rating of good or excellent.
Discussion:
This multidisciplinary case on dehydration can be used early in medical education to introduce students to clinical scenarios while learning fundamental science content. An integrated approach to medical content and versatility with regard to class size make this case a valuable teaching tool.
Related Concept Videos
Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...
Dehydration of Aldols to Enals: Base-Catalyzed Aldol Condensation
Student t Distribution
The Student t distribution was developed by William S. Goset (1876–1937) of the...
Microsoft Excel: Student's t-Test
To conduct a t-test in Excel, use the T.TEST function or the "Data...
Acid-Catalyzed Dehydration of Alcohols to Alkenes
Comparing Experimental Results: Student's t-Test

