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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
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Traverse angle computations are a critical component of surveying, used to compute the internal angles within a closed traverse. A traverse consists of a series of connected lines forming a closed loop, often used for land boundary delineation or mapping. Calculating the internal angles ensures accuracy in the traverse geometry and is essential for checking survey data integrity.The process begins with known azimuths and bearings of the traverse sides. Internal angles at each vertex are...
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Consider a cylindrical shaft with a length denoted by L and a consistent cross-sectional radius referred to as r. This shaft undergoes a torque at the free end. The highest shearing strain within the shaft is directly proportional to the twist angle and the radial distance from the shaft axis. When the shaft behaves elastically, this shearing strain can be articulated using variables such as the applied torque, radial distance, the polar moment of inertia, and the modulus of rigidity. By...
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Endoscopic cyclophotocoagulation (ECP) for open angle glaucoma and primary angle closure.

Márta Tóth1, Anupa Shah, Kuang Hu

  • 1Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London, UK, EC1V 2PD.

The Cochrane Database of Systematic Reviews
|February 26, 2019
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Summary
This summary is machine-generated.

Endoscopic cyclophotocoagulation (ECP) is a surgical treatment for glaucoma. Currently, there is insufficient high-quality evidence to confirm its efficacy and safety for open-angle glaucoma and primary angle closure.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Glaucoma Management

Background:

  • Glaucoma is a primary cause of irreversible blindness globally.
  • Minimally invasive surgical techniques are emerging treatments for glaucoma progression.
  • Endoscopic cyclophotocoagulation (ECP) is a cyclodestructive procedure developed in 1992.

Purpose of the Study:

  • To evaluate the efficacy and safety of ECP.
  • To assess ECP in patients with open-angle glaucoma (OAG) and primary angle closure.
  • To determine effectiveness in cases inadequately controlled by medication.

Main Methods:

  • Searched multiple databases including Cochrane CENTRAL, MEDLINE, Embase, and clinical trial registries up to July 2018.
  • Included randomized controlled trials (RCTs) comparing ECP to other surgical, laser, or medical treatments.
  • Planned data extraction and analysis focusing on drop-free status, intraocular pressure (IOP) reduction, and complications.

Main Results:

  • One ongoing study (ChiCTR-TRC-14004233) was identified, comparing combined phacoemulsification with ECP to phacoemulsification alone in primary angle closure glaucoma.
  • This study involves 50 participants, with recruitment completed and data collection in progress.
  • Primary outcomes for the ongoing study are intraocular pressure (IOP) and the number of IOP-lowering drugs.

Conclusions:

  • No high-quality evidence currently exists for the efficacy and safety of ECP in OAG and primary angle closure.
  • Further well-designed RCTs are necessary.
  • Medium and long-term outcomes of ECP require rigorous investigation.