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Updated: Jan 28, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrioventricular block can be used as a risk predictor of clinical atrial fibrillation
Xiao Zhao1, Chaofeng Sun2, Miaomiao Cao2
1Health Science Center, Xi'an Jiaotong University, Xi'an, P.R.China.
Insights
Atrioventricular block (AVB) is linked to atrial fibrillation (AF). Specifically, second-degree AVB shows the strongest association, suggesting AVB may be a risk factor for AF development.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Atrial fibrillation (AF) is a prevalent cardiac arrhythmia, contributing significantly to hospital admissions.
- Atrioventricular block (AVB) involves conduction abnormalities within the heart's electrical system.
- The association between AVB and AF remains a subject of ongoing research and debate.
Purpose of the Study:
- To investigate the correlation between atrioventricular block (AVB) and atrial fibrillation (AF).
- To identify which specific type of AVB exhibits the strongest association with AF.
Main Methods:
- A retrospective analysis of 1345 patients was conducted.
- Patients were classified based on atrioventricular block (AVB) criteria.
- A final cohort of 1243 patients (679 with AF, 564 without AF) was analyzed for comparative outcomes.
Main Results:
- All three types of atrioventricular block (AVB) were found at significantly higher rates in the atrial fibrillation (AF) group compared to the non-AF group.
- First-degree AVB showed a relative statistical risk of 1.927 for AF occurrence (P < 0.05).
- Second-degree AVB had the highest incidence in the AF group (9.87%) with a significant statistical risk of 16.845 (P < 0.000), followed by third-degree AVB with a risk of 17.599 (P < 0.000).
Conclusions:
- The prevalence of all three types of atrioventricular block (AVB) is significantly elevated in patients with atrial fibrillation (AF).
- Second-degree AVB demonstrates the highest incidence rate among AVB types within the AF cohort.
- Atrioventricular block (AVB) should be considered a potential risk factor for the development of atrial fibrillation (AF).
Background:
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with its incidence making up nearly one-third of all hospital admissions. Atrioventricular block (AVB) is a conduction abnormality along the atrioventricular node or the His-Purkinje system. The relationship between atrioventricular conduction block and AF is controversial.
Hypothesis:
This study is designed to observe whether there is a correlation between AVB and AF, and which type of AVB has the most obvious correlation with AF.
Methods:
This study retrospectively reviewed 1345 patients. We classified the AVB according to the AVB classification criteria. One hundred and two patients were excluded, and the final total sample size was 1243 patients, including 679 patients in the AF group (378, 55.7% males) and 564 patients in the non-AF group (287, 50.8% males). AF group and non-AF group were compared to observe the relationship between AVB and AF.
Results:
The I AVB have a relative statistical risk of 1.927 (95% confidence interval [CI]: 1.160-3.203, P < 0.05) with the occurrence of AF. II AVB occupied the largest proportion, accounting for 67 cases (9.87%), and the statistical risk of II AVB in AF is 16.845 (95% CI: 6.099-46.524, P < 0.000). III AVB has a comparative statistical risk of 17.599 (95% CI: 4.212-73.541, P < 0.000).
Conclusions:
The three types of AVB in the AF group were significantly higher than that in the non-AF group. II AVB has the highest incidence rate compared with other types of AVB in the AF group. AVB can be used as a risk factor for AF occurrence.
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