Related Experiment Video

Updated: Jan 28, 2026

Establishing In Vitro Models of Dorsal Root Ganglia Culture: Complementary Approaches for Investigating Cancer-Nerve Crosstalk
11:26

Establishing In Vitro Models of Dorsal Root Ganglia Culture: Complementary Approaches for Investigating Cancer-Nerve Crosstalk

Published on: July 11, 2025

1.7K

Skin cancer prevention: a review of current topical options complementary to sunscreens

A Rosenthal1,2, M Stoddard2, L Chipps2,3

  • 1Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Journal of the European Academy of Dermatology and Venereology : JEADV
|February 26, 2019
PubMed

Insights

Non-melanoma skin cancer (NMSC) is rising globally, necessitating new prevention strategies. Emerging topical treatments targeting DNA repair and precancerous cells show promise beyond traditional sunscreens.

Area of Science:

  • Dermatology
  • Oncology
  • Molecular Biology

Background:

  • Global incidence of non-melanoma skin cancer (NMSC) is increasing significantly.
  • Despite widespread sunscreen use, NMSC diagnoses continue to rise, indicating a need for supplementary preventative measures.
  • Millions are treated annually for NMSC, highlighting the public health burden.

Purpose of the Study:

  • To explore novel topical products for skin cancer prevention.
  • To identify strategies that complement sunscreen use.
  • To investigate emerging treatments beyond traditional photoprotection.

Main Methods:

  • Review of current literature on NMSC incidence and prevention.
  • Analysis of emerging topical product categories.
  • Assessment of mechanisms of action for novel skincare ingredients.

Main Results:

  • New topical products offer potential for enhanced skin cancer prevention.
  • These products focus on mechanisms like DNA repair, transcription modulation, and anti-inflammation.
  • Targeting precancerous cells represents a novel preventative approach.

Conclusions:

  • Emerging topical treatments may play a crucial role in future NMSC prevention strategies.
  • These advanced formulations offer a promising alternative or adjunct to conventional sunscreens.
  • Further research into these novel products is warranted to combat rising skin cancer rates.

More Related Videos

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

898
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.9K

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.1K
Complementary DNA01:44

Complementary DNA

Overview
31.5K
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.8K
Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.2K
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K