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Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
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Noncompaction-like membranous structure in left ventricle
Ozben Ceylan1, Didem Arman2, Nursu Kara2
1Department of Pediatric Cardiology, Istanbul Education and Research Hospital, Istanbul, Turkey.
Echocardiography (Mount Kisco, N.Y.)
|February 26, 2019
Summary
A rare cardiac anomaly, a membranous structure in the left ventricle, was identified in a newborn. This finding is considered a variant of left ventricular noncompaction, requiring ongoing pediatric cardiology follow-up.
Area of Science:
- Pediatric Cardiology
- Neonatal Echocardiography
- Congenital Heart Disease
Background:
- Routine examination of a 22-day-old infant revealed a subtle systolic murmur.
- The infant had no other observed clinical abnormalities or malformations.
Observation:
- Echocardiography identified a distinct membranous structure originating from the left ventricular apex.
- This structure extended to the mitral chords and papillary muscles, visualized in apical four-chamber and parasternal long-axis views.
Findings:
- The observed cardiac anomaly was diagnosed as a potential variant of left ventricular noncompaction.
- This diagnosis was based on the unique anatomical characteristics identified via echocardiography.
Implications:
- This case highlights the importance of echocardiography in diagnosing subtle congenital heart anomalies in neonates.
- Continued monitoring in a pediatric cardiology setting is essential for managing this left ventricular variant.
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