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Characterizing adolescents with heavy menstrual bleeding and generalized joint hypermobility

Nicole E Kendel1, Fareeda W Haamid2, Myra Christian-Rancy3

  • 1Pediatric Residency Program, Nationwide Children's Hospital/The Ohio State University, Ohio, Columbus.

Pediatric Blood & Cancer
|February 26, 2019
PubMed

Patients with generalized joint hypermobility (JHM) may experience excessive bruising/bleeding, with heavy menstrual bleeding (HMB) commonly reported. We performed a retrospective review of 30 adolescents seen in a Young Women's Hematology Clinic with both HMB and JHM. We found that (1) a significant delay (mean 36 months, range 5-72) occurred between menarche and referral to specialty care, (2) HMB had moderate to severe impact on school and physical activities in 60% of patients, and (3) most patients (68%) required escalation of their initial therapy. We suggest providers consider JHM as a risk factor for a more complex clinical course.

Keywords:
Ehlers-Danlos syndromeadolescentbleeding disorders other than hemophiliamenorrhagia

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